genetic engineering


4. The DNA

• DNA of a gene encodes the chemical structure of a protein

• the genetic code determines the sequence of the amino acids that make up protein

Genes are contained in DNA. Lets now look at the structure of DNA.

  • nucleotide
  • nitrogenous base
  • deoxyribose sugar
  • phosphate group
  • phosphate backbone

NEOCLEOTIDES

• the structural unit of nucleotide chains forming nucleic acids

• nucleotides play important roles in cellular energy transport and transformations and in enzyme regulation

NITROGENOUS BASE

  • organic compounds that owe their basic properties to the lone pair (an electron pair without bonding or sharing with other atoms. It often exhibits a negative polar character with its high charge density.) of electrons of a nitrogen atom.
  • Complementary Base Pairing

• -A pairs with T by 2 hydrogen bonds

-C pairs with G by 3 hydrogen bonds

• Adenine (A) — Chemical formula – C5H5N5 Molecular mass – 135.13 g/molMelting point – 360 – 365 °C

Source: http://hal.wzw.tum.de/genglos/images/adenine.gif

A binds to T to assist in stabilizing the nucleic acid structures

• Thymine (T) — Chemical formula – C5H6N2O2 Molecular – 126g/molMelting point – 316 – 317 °C

Source: http://www.ca.uky.edu/agripedia/glossary/agriart/thymine.gif

• Cytosine (C) —Chemical formula – C4H5N3O Molecular mass – 111.1g/molMelting point – 320 – 325 °C

Source: http://www.ca.uky.edu/agripedia/GLOSSARY/agriart/cytosine.gif

 

• Guanine (G) —Chemical formula – C5H5N5O , Molecular mass – 151.13 g/mol Melting point – 360 °C

 

Source: http://www.edu.upmc.fr/sdv/masselot_05001/annexe/images/pic004.jpg

 

A picture of DNA :

Source: http://www.biologycorner.com/resources/DNA-colored.gif


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